Short answer: Rejuran Eye uses polynucleotides as a targeted skin-quality treatment, while PRF is prepared from your own blood and contains platelets within a fibrin matrix. Both may be considered for fine, crepey or weakened under-eye skin, but they are different treatments and neither is suitable for every cause of dark circles, puffiness or hollowing.
Why the Under-Eye Area Needs Assessment
“Tired under eyes” can describe several different concerns. Fine lines, thin skin, pigmentation, visible vessels, fluid retention, fat pads, bone structure and hollowing may all contribute. A treatment that supports skin quality will not necessarily correct a structural hollow or prominent bag.
A consultation should identify the main cause before comparing treatment options. You can also explore the clinic’s broader eye area treatment information.
What Is Rejuran Eye?
Rejuran Eye is designed for the delicate under-eye area and uses polynucleotides to support skin repair, hydration and resilience. The goal is to improve the quality of the skin rather than add significant volume or restrict movement.
It may be assessed when the concern involves:
- Fine or crepey under-eye texture
- Thin or dehydrated-looking skin
- Early visible changes in skin quality
- Mild darkness where thin skin is a contributing factor
Small raised areas, swelling, redness or bruising may occur after treatment. Outcomes develop gradually and vary.
What Is PRF Under the Eyes?
PRF treatment, or platelet-rich fibrin, is produced from a small sample of your own blood. The preparation contains platelets and a fibrin network that supports a gradual release of signalling proteins involved in the body’s repair processes.
PRF may be assessed for delicate under-eye skin when the goal is gradual, autologous support rather than a synthetic product. Research into injectable PRF for facial rejuvenation is promising, but study methods are still varied and individual outcomes cannot be guaranteed. A clinical study is available through PubMed.
Rejuran Eye and PRF Compared
| Factor | Rejuran Eye | PRF |
|---|---|---|
| Material | Polynucleotide-based formulation | Prepared from the client’s own blood |
| Primary focus | Under-eye skin quality and resilience | Autologous regenerative support |
| Changes | Gradual and skin-focused | Gradual and dependent on individual biology |
| Planning | Usually discussed as a treatment series | May also involve a planned series |
What Neither Treatment Can Promise
Neither treatment can guarantee removal of dark circles, bags, lines or hollows. If the concern is mainly pigment, prominent vessels, fluid retention or structural volume loss, another plan may be more appropriate. Sometimes the safest recommendation is not to treat.
Frequently Asked Questions
Is Rejuran Eye the same as PRF?
No. Rejuran Eye uses a polynucleotide formulation. PRF is prepared from the client’s own blood.
Which is better for crepey under eyes?
Either may be considered, but the better option depends on skin quality, anatomy, health, treatment history and goals.
Does PRF fill under-eye hollows?
PRF may create subtle changes, but it should not be treated as a guaranteed substitute for a structural volume treatment. Assessment is essential.
Can Rejuran Eye and PRF be combined?
A clinician may discuss a staged plan in selected cases. Timing and suitability must be personalised.
That Face Place offers consultation-led Rejuran Eye and PRF treatments at its Palm Beach clinic. Contact the team to arrange an individual assessment.

